Catalog/Longevity
Longevity
Glutathione
GSH, γ-glutamyl-cysteinyl-glycine
The principal intracellular thiol buffer, studied as an antioxidant and xenobiotic-conjugation cofactor.
Sequence
- Hydrophobic
- Polar
- Charged
γ-glutamyl isopeptide, not a standard α-peptide bond at Glu–Cys
ECG
- CAS
- 70-18-8
- Formula
- C10H17N3O6S
- Mass (g/mol)
- 307.32
- Half-life
- Minutes in plasma
- Form
- Lyophilized
- Purity
- ≥98%
Mechanism
GSH reduces peroxides via glutathione peroxidase and conjugates electrophiles via GSTs. The thiol is the chemistry.
Research notes
Oxidation to GSSG is the failure mode. Keep air out of working stocks.
Lyophilized: −20 °C. Reconstituted: use promptly; thiols oxidize.
Typical reconstitution
Catalog convenience numbers — not a protocol. Vial 1500 mg in 10 mL; default draw 100000 mcg.