Catalog/Longevity
Longevity
SS-31
Elamipretide, Bendavia
A mitochondria-targeted tetrapeptide that associates with cardiolipin and is studied in electron-transport and ischemia models.
Sequence
- Hydrophobic
- Polar
- Charged
Mitochondria-targeted tetrapeptide; Dmt = 2,6-dimethyltyrosine
DArgDmtLysPheNH2
- CAS
- 736992-69-5
- Formula
- C32H49N9O5
- Mass (g/mol)
- 639.79
- Half-life
- ~4 h
- Form
- Lyophilized acetate
- Purity
- ≥98% HPLC
Mechanism
SS-31 binds cardiolipin on the inner mitochondrial membrane and is reported to stabilize cristae and reduce ROS in injured mitochondria.
Research notes
One of the few mitochondrial peptides with a named clinical candidate (elamipretide).
Lyophilized: −20 °C, dry.
Typical reconstitution
Catalog convenience numbers — not a protocol. Vial 10 mg in 2 mL; default draw 500 mcg.