Catalog/Metabolic

Metabolic

Semaglutide

GLP-1 receptor agonist

A long-acting GLP-1 receptor agonist used to study incretin signaling and gastric emptying.

Sequence

  • Hydrophobic
  • Polar
  • Charged

Human GLP-1 analog with Aib8 and C18 fatty-diacid acylation

HAibEGTFTSDVSSYLEGQAAK(C18diacidγGlu)EFIAWLVRGRG
CAS
910463-68-2
Formula
C187H291N45O59
Mass (g/mol)
4113.58
Half-life
~7 days
Form
Lyophilized
Purity
≥98% HPLC

Mechanism

C18 diacid acylation enables albumin binding. Receptor activation on pancreatic and hypothalamic circuits is the published mechanism.

Research notes

A registered medicine exists; this listing is research-grade powder only.

Lyophilized: −20 °C. Protect from light.

Typical reconstitution

Catalog convenience numbers — not a protocol. Vial 10 mg in 2 mL; default draw 250 mcg.

Adjacent