Catalog/Cognitive
Cognitive
PT-141
Bremelanotide
A cyclic melanocortin-receptor agonist studied in hypothalamic signaling; a registered medicine exists under another label.
Sequence
- Hydrophobic
- Polar
- Charged
Cyclic melanocortin agonist; research listing only
AcNlecyclo[AspHisDPheArgTrpLys]
- CAS
- 189691-06-3
- Formula
- C50H68N14O10
- Mass (g/mol)
- 1025.18
- Half-life
- ~2–3 h
- Form
- Lyophilized acetate
- Purity
- ≥98% HPLC
Mechanism
Agonizes MC3R/MC4R in the CNS. Distinct from the linear α-MSH fragment KPV.
Research notes
Research-grade powder is not the approved drug. Handle as a cyclic peptide.
Lyophilized: −20 °C, dark. Tryptophan is oxidation-prone.
Typical reconstitution
Catalog convenience numbers — not a protocol. Vial 10 mg in 2 mL; default draw 500 mcg.